Selectivity of Lewy body protein interactions along the aggregation pathway of α-synuclein
To better understand the specific cascade of protein interactions that lead to the pathological aggregation of α-synuclein (wild-type and mutant forms), Leitão et al. present a method to measure interactions of monomeric, oligomeric, and fibrillar forms of α-syn with 65 proteins that were previously...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-09-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-021-02624-x |