Host cell invasion and virulence mediated by Candida albicans Ssa1.

Candida albicans Ssa1 and Ssa2 are members of the HSP70 family of heat shock proteins that are expressed on the cell surface and function as receptors for antimicrobial peptides such as histatins. We investigated the role of Ssa1 and Ssa2 in mediating pathogenic host cell interactions and virulence....

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Main Authors: Jianing N Sun, Norma V Solis, Quynh T Phan, Jashanjot S Bajwa, Helena Kashleva, Angela Thompson, Yaoping Liu, Anna Dongari-Bagtzoglou, Mira Edgerton, Scott G Filler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-11-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2978716?pdf=render