ERK2-mediated phosphorylation of transcriptional coactivator binding protein PIMT/NCoA6IP at Ser298 augments hepatic gluconeogenesis.

PRIP-Interacting protein with methyl transferase domain (PIMT) serves as a molecular bridge between CREB-binding protein (CBP)/ E1A binding protein p300 (Ep300) -anchored histone acetyl transferase and the Mediator complex sub-unit1 (Med1) and modulates nuclear receptor transcription. Here, we repor...

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Main Authors: Bandish Kapadia, Navin Viswakarma, Kishore V L Parsa, Vasundhara Kain, Soma Behera, Sashidhara Kaimal Suraj, Phanithi Prakash Babu, Anand Kar, Sunanda Panda, Yi-jun Zhu, Yuzhi Jia, Bayar Thimmapaya, Janardan K Reddy, Parimal Misra
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3866170?pdf=render