Biphasic change of tau (τ) in mice as arterial load acutely increased with phenylephrine injection.

Diastolic dysfunction is the hemodynamic hallmark of hypertensive heart disease. Tau (τ) has been used to describe left ventricle relaxation. The relationship between τ and afterload has been controversial. Our goal was to demonstrate this relationship in mice, because genetically-modified mouse mod...

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Bibliographic Details
Main Authors: Bo Yang, Douglas F Larson, James Ranger-Moore
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3620408?pdf=render