Corneal alternations induced by topical application of benzalkonium chloride in rabbit.

Benzalkonium chloride (BAC) is the most common preservative in ophthalmic preparations. Here, we investigated the corneal alternations in rabbits following exposure to BAC. Twenty-four adult male New Zealand albino rabbits were randomly divided into three groups. BAC at 0.01%, 0.05%, or 0.1% was app...

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Bibliographic Details
Main Authors: Wensheng Chen, Zhiyuan Li, Jiaoyue Hu, Zhenhao Zhang, Lelei Chen, Yongxiong Chen, Zuguo Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3192149?pdf=render