Iron-dependent apoptosis causes embryotoxicity in inflamed and obese pregnancy

Iron is essential during pregnancy for embryo and placental development and maternal health. However, in this study using mouse models, the authors demonstrate that excess maternal iron causes adverse embryo outcomes in pregnancies with underlying systemic inflammation.

Bibliographic Details
Main Authors: Allison L. Fisher, Veena Sangkhae, Kamila Balušíková, Nicolaos J. Palaskas, Tomas Ganz, Elizabeta Nemeth
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-24333-z