PTMsnp: A Web Server for the Identification of Driver Mutations That Affect Protein Post-translational Modification

PTMsnp: A Web Server for the Identification of Driver Mutations That Affect Protein Post-translational Modification

High-throughput sequencing technologies have identified millions of genetic mutations in multiple human diseases. However, the interpretation of the pathogenesis of these mutations and the discovery of driver genes that dominate disease progression is still a major challenge. Combining functional fe...

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Bibliographic Details
Main Authors: Di Peng, Huiqin Li, Bosu Hu, Hongwan Zhang, Li Chen, Shaofeng Lin, Zhixiang Zuo, Yu Xue, Jian Ren, Yubin Xie
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
protein post-translational modification
genetic mutations
Bayesian hierarchical model
driver genes
disease
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.593661/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2020.593661/full

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