BIRC2 Expression Impairs Anti-Cancer Immunity and Immunotherapy Efficacy

Summary: Immune checkpoint blockade (ICB) has led to therapeutic responses in some cancer patients for whom no effective treatment previously existed. ICB acts on T lymphocytes and other immune cells that are inactivated due to checkpoint signals that inhibit their infiltration and function within t...

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Bibliographic Details
Main Authors: Debangshu Samanta, Tina Yi-Ting Huang, Rima Shah, Yongkang Yang, Fan Pan, Gregg L. Semenza
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720310585