Requirement of the Dynein-Adaptor Spindly for Mitotic and Post-Mitotic Functions in Drosophila

Spindly was originally identified as a specific regulator of Dynein activity at the kinetochore. In early prometaphase, Spindly recruits the Dynein/Dynactin complex, promoting the establishment of stable kinetochore-microtubule interactions and progression into anaphase. While details of Spindly fun...

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Bibliographic Details
Main Authors: Giuliana D. Clemente, Matthew R. Hannaford, Hamze Beati, Katja Kapp, Jens Januschke, Eric R. Griffis, Hans-Arno J. Müller
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:Journal of Developmental Biology
Subjects:
Online Access:http://www.mdpi.com/2221-3759/6/2/9