The use of longitudinal 18F-FET MicroPET imaging to evaluate response to irinotecan in orthotopic human glioblastoma multiforme xenografts.

OBJECTIVES:Brain tumor imaging is challenging. Although 18F-FET PET is widely used in the clinic, the value of 18F-FET MicroPET to evaluate brain tumors in xenograft has not been assessed to date. The aim of this study therefore was to evaluate the performance of in vivo 18F-FET MicroPET in detectin...

Full description

Bibliographic Details
Main Authors: Mette K Nedergaard, Karina Kristoffersen, Signe R Michaelsen, Jacob Madsen, Hans S Poulsen, Marie-Thérése Stockhausen, Ulrik Lassen, Andreas Kjaer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4053391?pdf=render