Programming Native CRISPR Arrays for the Generation of Targeted Immunity
The adaptive immune system of prokaryotes, called CRISPR-Cas (clustered regularly interspaced short palindromic repeats and CRISPR-associated genes), results in specific cleavage of invading nucleic acid sequences recognized by the cell’s “memory” of past encounters. Here, we exploited the propertie...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
American Society for Microbiology
2016-05-01
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| Series: | mBio |
| Online Access: | http://mbio.asm.org/cgi/content/full/7/3/e00202-16 |