SSADH Variants Increase Susceptibility of U87 Cells to Mitochondrial Pro-Oxidant Insult
Succinate semialdehyde dehydrogenase (SSADH) is a mitochondrial enzyme, encoded by <i>ALDH5A1</i>, mainly involved in γ-aminobutyric acid (GABA) catabolism and energy supply of neuronal cells, possibly contributing to antioxidant defense. This study aimed to further investigate the antio...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-06-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/21/12/4374 |