Role of microRNA-182 in posterior uveal melanoma: regulation of tumor development through MITF, BCL2 and cyclin D2.

Role of microRNA-182 in posterior uveal melanoma: regulation of tumor development through MITF, BCL2 and cyclin D2.

MicroRNAs (miRNAs) are endogenous small non-coding RNAs that play central roles in diverse pathological processes. In this study, we investigated the effect of microRNA-182 (miR-182) on the development of posterior uveal melanomas. Initially, we demonstrated that miR-182 expression was dependent on...

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Bibliographic Details
Main Authors: Dongsheng Yan, Xiang Da Dong, Xiaoyan Chen, Shasha Yao, Lihua Wang, Jiao Wang, Chao Wang, Dan-Ning Hu, Jia Qu, LiLi Tu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3407171?pdf=render

Internet

http://europepmc.org/articles/PMC3407171?pdf=render

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