Histological comparison of arterial thrombi in mice and men and the influence of Cl-amidine on thrombus formation.

Histological comparison of arterial thrombi in mice and men and the influence of Cl-amidine on thrombus formation.

Medical treatment of arterial thrombosis is mainly directed against platelets and coagulation factors, and can lead to bleeding complications. Novel antithrombotic therapies targeting immune cells and neutrophil extracellular traps (NETs) are currently being investigated in animals. We addressed whe...

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Bibliographic Details
Main Authors: Julia Novotny, Sue Chandraratne, Tobias Weinberger, Vanessa Philippi, Konstantin Stark, Andreas Ehrlich, Joachim Pircher, Ildiko Konrad, Paul Oberdieck, Anna Titova, Qendresa Hoti, Irene Schubert, Kyle R Legate, Nicole Urtz, Michael Lorenz, Jaroslav Pelisek, Steffen Massberg, Marie-Luise von Brühl, Christian Schulz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5749862?pdf=render

Internet

http://europepmc.org/articles/PMC5749862?pdf=render

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