Focal distribution of hepatitis C virus RNA in infected livers.

BACKGROUND: Hepatitis C virus (HCV) is a plus-strand RNA virus that replicates by amplification of genomic RNA from minus strands leading to accumulation of almost one thousand copies per cell under in vitro cell culture conditions. In contrast, HCV RNA copy numbers in livers of infected patients ap...

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Bibliographic Details
Main Authors: J David Stiffler, Minhhuyen Nguyen, Ji A Sohn, Chen Liu, David Kaplan, Christoph Seeger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2722721?pdf=render