SODB1 is essential for Leishmania major infection of macrophages and pathogenesis in mice.

Leishmania species are sand fly-transmitted protozoan parasites that cause leishmaniasis, neglected tropical diseases that affect millions of people. Leishmania amastigotes must overcome a variety of host defenses, including reactive oxygen species (ROS) produced by the NADPH oxidase. Leishmania spe...

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Bibliographic Details
Main Authors: Bennett J Davenport, Casey G Martin, Stephen M Beverley, David J Orlicky, Andres Vazquez-Torres, Thomas E Morrison
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-10-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC6224164?pdf=render