Knockdown of the translocon protein EXP2 in Plasmodium falciparum reduces growth and protein export.

Malaria parasites remodel their host erythrocytes to gain nutrients and avoid the immune system. Host erythrocytes are modified by hundreds of effector proteins exported from the parasite into the host cell. Protein export is mediated by the PTEX translocon comprising five core components of which E...

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Bibliographic Details
Main Authors: Sarah C Charnaud, Rasika Kumarasingha, Hayley E Bullen, Brendan S Crabb, Paul R Gilson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6237293?pdf=render