Contributions of HA1 and HA2 Subunits of Highly Pathogenic Avian Influenza Virus in Induction of Neutralizing Antibodies and Protection in Chickens

Contributions of HA1 and HA2 Subunits of Highly Pathogenic Avian Influenza Virus in Induction of Neutralizing Antibodies and Protection in Chickens

Highly pathogenic avian influenza virus (HPAIV) subtype H5N1 causes a devastating disease in poultry. Vaccination is an effective method of controlling avian influenza virus (AIV) infection in poultry. The hemagglutinin (HA) protein is the major determinant recognized by the immune system of the hos...

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Bibliographic Details
Main Authors: Edris Shirvani, Anandan Paldurai, Berin P. Varghese, Siba K. Samal
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Microbiology
Subjects:
highly pathogenic avian influenza virus
hemagglutinin subunits
protective epitopes
native conformation
poultry vaccines
natural host model
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.01085/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2020.01085/full

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