PDE9A is Expressed in the Inner Retina and Contributes to the Normal Shape of the Photopic ERG Waveform

PDE9A is Expressed in the Inner Retina and Contributes to the Normal Shape of the Photopic ERG Waveform

The ubiquitous second messenger cGMP is synthesized by guanylyl cyclase and hydrolyzed by phosphodiesterase (PDE). cGMP mediates numerous signaling pathways in multiple tissues. In the retina, cGMP regulates signaling in nearly every cell class including photoreceptors, bipolar cells, amacrine cells...

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Bibliographic Details
Main Authors: Anuradha eDhingra, Shanti R Tummala, Arkady eLyubarsky, Noga eVardi
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-06-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Amacrine Cells
Ciliary Body
Cyclic GMP
erg
serial inhibition
cone pathway
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2014.00060/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnmol.2014.00060/full

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