ACTH depresses delta 6 and delta 5 desaturation activity in rat adrenal gland and liver.

The in vivo and in vitro effect of ACTH on the biosynthesis of polyunsaturated fatty acid of rat adrenal gland and liver was studied. The administration of ACTH to intact rats produced a significant decrease in the conversion of [1-14C]linoleic acid to gamma-linolenic acid, [1-14C]alpha-linolenic ac...

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Bibliographic Details
Main Authors: E C Mandon, I N de Gómez Dumm, M J de Alaníz, C A Marra, R R Brenner
Format: Article
Language:English
Published: Elsevier 1987-12-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520385709