Ergosta-7,9(11),22-trien-3β-ol Alleviates Intracerebral Hemorrhage-Induced Brain Injury and BV-2 Microglial Activation

Ergosta-7,9(11),22-trien-3β-ol Alleviates Intracerebral Hemorrhage-Induced Brain Injury and BV-2 Microglial Activation

Intracerebral hemorrhage (ICH) is a devastating neurological disorder characterized by an exacerbation of neuroinflammation and neuronal injury, for which few effective therapies are available at present. Inhibition of excessive neuroglial activation has been reported to alleviate ICH-related brain...

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Bibliographic Details
Main Authors: Po-Jen Hsueh, Mong-Heng Wang, Che-Jen Hsiao, Chih-Kuang Chen, Fan-Li Lin, Shu-Hsien Huang, Jing-Lun Yen, Ping-Huei Tsai, Yueh-Hsiung Kuo, George Hsiao
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Molecules
Subjects:
ergosta-7,9(11),22-trien-3β-ol
intracerebral hemorrhage
COX-2
MMP-9
microglia
JNK
Online Access:https://www.mdpi.com/1420-3049/26/10/2970

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https://www.mdpi.com/1420-3049/26/10/2970

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