Neuromuscular Plasticity in a Mouse Neurotoxic Model of Spinal Motoneuronal Loss

Neuromuscular Plasticity in a Mouse Neurotoxic Model of Spinal Motoneuronal Loss

Despite the relevant research efforts, the causes of amyotrophic lateral sclerosis (ALS) are still unknown and no effective cure is available. Many authors suggest that ALS is a multi-system disease caused by a network failure instead of a cell-autonomous pathology restricted to motoneurons. Althoug...

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Bibliographic Details
Main Authors: Rosario Gulino, Nunzio Vicario, Maria A.S. Giunta, Graziana Spoto, Giovanna Calabrese, Michele Vecchio, Massimo Gulisano, Giampiero Leanza, Rosalba Parenti
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:International Journal of Molecular Sciences
Subjects:
neurodegeneration
spinal cord
gastrocnemius muscle
CTB-Saporin
neuronal plasticity
AMPA receptor
motoneuron
astrocyte
Online Access:https://www.mdpi.com/1422-0067/20/6/1500

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https://www.mdpi.com/1422-0067/20/6/1500

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