Rescue of Retinal Degeneration in rd1 Mice by Intravitreally Injected Metformin

Rescue of Retinal Degeneration in rd1 Mice by Intravitreally Injected Metformin

Retinitis pigmentosa (RP) is a progressive hereditary retinal degenerative disease in which photoreceptor cells undergo degeneration and apoptosis, eventually resulting in irreversible loss of visual function. Currently, no effective treatment exists for this disease. Neuroprotection and inflammatio...

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Bibliographic Details
Main Authors: Luodan A, Ting Zou, Juncai He, Xia Chen, Dayu Sun, Xiaotang Fan, Haiwei Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Molecular Neuroscience
Subjects:
metformin
retinitis pigmentosa
microglia
crystallin
mice
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2019.00102/full

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https://www.frontiersin.org/article/10.3389/fnmol.2019.00102/full

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