Mechanisms of caffeine-induced inhibition of UVB carcinogenesis

Mechanisms of caffeine-induced inhibition of UVB carcinogenesis

Sunlight-induced nonmelanoma skin cancer is the most prevalent cancer in the United States with more than 2 million cases per year. Several studies have shown an inhibitory effect of caffeine administration on UVB-induced skin cancer in mice, and these studies are paralleled by epidemiology studies...

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Bibliographic Details
Main Authors: Allan H Conney, Yao-Ping eLu, You-Rong eLou, Masaoki eKawasumi, Paul eNghiem
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-06-01
Series:Frontiers in Oncology
Subjects:
Caffeine
Coffee
Sunlight-induced skin cancer
sunscreen
ATR inhibition
upregulation of p53
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00144/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00144/full

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