A bipartite iron-dependent transcriptional regulation of the tryptophan salvage pathway in Chlamydia trachomatis

A bipartite iron-dependent transcriptional regulation of the tryptophan salvage pathway in Chlamydia trachomatis

During infection, pathogens are starved of essential nutrients such as iron and tryptophan by host immune effectors. Without conserved global stress response regulators, how the obligate intracellular bacterium Chlamydia trachomatis arrives at a physiologically similar ‘persistent’ state in response...

Full description

Bibliographic Details
Main Authors: Nick D Pokorzynski, Amanda J Brinkworth, Rey Carabeo
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-04-01
Series:eLife
Subjects:
Chlamydia trachomatis
stress response
tryptophan biosynthesis
iron-dependent regulation
transcription
repression
Online Access:https://elifesciences.org/articles/42295

Internet

https://elifesciences.org/articles/42295

Similar Items