Update on Denosumab Treatment in Postmenopausal Women with Osteoporosis

Denosumab, a fully human recombinant monoclonal antibody to the receptor activator of nuclear factor-κB ligand (RANKL), blocks binding of RANKL to the RANK receptor, found on the surface of osteoclasts and osteoclast precursors, resulting in decreased bone resorption. Subcutaneous denosumab administ...

Full description

Bibliographic Details
Main Author: Yong-Ki Min
Format: Article
Language:English
Published: Academya Publishing Co. 2015-03-01
Series:Endocrinology and Metabolism
Subjects:
Online Access:http://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-30-19.pdf