Update on Denosumab Treatment in Postmenopausal Women with Osteoporosis
Denosumab, a fully human recombinant monoclonal antibody to the receptor activator of nuclear factor-κB ligand (RANKL), blocks binding of RANKL to the RANK receptor, found on the surface of osteoclasts and osteoclast precursors, resulting in decreased bone resorption. Subcutaneous denosumab administ...
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Format: | Article |
Language: | English |
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Academya Publishing Co.
2015-03-01
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Series: | Endocrinology and Metabolism |
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Online Access: | http://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-30-19.pdf |