Effect of melatonin administration on the PER1 and BMAL1 clock genes in patients with Parkinson’s disease

Effect of melatonin administration on the PER1 and BMAL1 clock genes in patients with Parkinson’s disease

Sleep disorders are a widespread condition in patients with Parkinson's disease (PD), which has been linked to a deregulation of the circadian cycle and therefore of the clock genes. The aim of this study was to evaluate the effect of melatonin (MEL) on the PER1 and BMAL1 clock genes in patient...

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Bibliographic Details
Main Authors: D.L. Delgado-Lara, G.V. González-Enríquez, B.M. Torres-Mendoza, H. González-Usigli, J. Cárdenas-Bedoya, M.A. Macías-Islas, A. Celis de la Rosa, A. Jiménez-Delgado, F. Pacheco-Moisés, J.A. Cruz-Serrano, G.G. Ortiz
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Melatonin
Clock genes
BMAL1gene
PER1gene
Parkinson's disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220306788

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http://www.sciencedirect.com/science/article/pii/S0753332220306788

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