High-resolution temporal and regional mapping of MAPT expression and splicing in human brain development.

The microtubule associated protein tau plays a critical role in the pathogenesis of neurodegenerative disease. Recent studies suggest that tau also plays a role in disorders of neuronal connectivity, including epilepsy and post-traumatic stress disorder. Animal studies have shown that the MAPT gene,...

Full description

Bibliographic Details
Main Authors: Marco M Hefti, Kurt Farrell, SoongHo Kim, Kathryn R Bowles, Mary E Fowkes, Towfique Raj, John F Crary
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5892924?pdf=render