The Role of T Cell Costimulation via DNAM-1 in Kidney Transplantation.

DNAX accessory protein-1 (DNAM-1, CD226) is a co-stimulatory and adhesion molecule expressed mainly by natural killer cells and T cells. DNAM-1 and its two ligands CD112 and CD155 are important in graft-versus-host disease, but their role in solid organ transplantation is largely unknown. We investi...

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Bibliographic Details
Main Authors: Anna K Kraus, Jin Chen, Ilka Edenhofer, Inga Ravens, Ariana Gaspert, Pietro E Cippà, Steffen Mueller, Rudolf P Wuthrich, Stephan Segerer, Guenter Bernhardt, Thomas Fehr
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4739582?pdf=render