The influence of sex, genotype, and dose on serum and hippocampal cytokine levels in juvenile mice developmentally exposed to a human-relevant mixture of polychlorinated biphenyls

The influence of sex, genotype, and dose on serum and hippocampal cytokine levels in juvenile mice developmentally exposed to a human-relevant mixture of polychlorinated biphenyls

Polychlorinated biphenyls (PCBs) are pervasive environmental contaminants implicated as risk factors for neurodevelopmental disorders (NDDs). Immune dysregulation is another NDD risk factor, and developmental PCB exposures are associated with early life immune dysregulation. Studies of the immunomod...

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Bibliographic Details
Main Authors: Lauren Matelski, Kimberly P. Keil Stietz, Sunjay Sethi, Sandra L. Taylor, Judy Van de Water, Pamela J. Lein
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Current Research in Toxicology
Subjects:
CGG repeat expansion mutation
Chemokines
fmr1
Neurodevelopmental disorders
Neuroimmune interactions
Ryanodine receptor
Online Access:http://www.sciencedirect.com/science/article/pii/S2666027X20300116

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http://www.sciencedirect.com/science/article/pii/S2666027X20300116

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