Competition between Heterochromatic Loci Allows the Abundance of the Silencing Protein, Sir4, to Regulate de novo Assembly of Heterochromatin.

Changes in the locations and boundaries of heterochromatin are critical during development, and de novo assembly of silent chromatin in budding yeast is a well-studied model for how new sites of heterochromatin assemble. De novo assembly cannot occur in the G1 phase of the cell cycle and one to two...

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Bibliographic Details
Main Authors: Michelle L Larin, Katherine Harding, Elizabeth C Williams, Noel Lianga, Carole Doré, Sophie Pilon, Éric Langis, Corey Yanofsky, Adam D Rudner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-11-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4654584?pdf=render