The in vitro and in vivo depigmenting activity of pterostilbene through induction of autophagy in melanocytes and inhibition of UVA-irradiated α-MSH in keratinocytes via Nrf2-mediated antioxidant pathways
Pterostilbene (Pt) is a natural polyphenol found in blueberries and several grape varieties. Pt's pharmacological importance was well documented. Nevertheless, the depigmenting effects are not demonstrated. We evaluated the Pt's depigmenting effects through autophagy induction in B16F10 ce...
Main Authors: | You-Cheng Hseu, PhD, Yugandhar Vudhya Gowrisankar, PhD, Li-Wei Wang, MS, Yan-Zhen Zhang, MS, Xuan-Zao Chen, MS, Pei-Jane Huang, PhD, Hung-Rong Yen, PhD, Hsin-Ling Yang, PhD |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2021-08-01
|
Series: | Redox Biology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213231721001658 |
Similar Items
-
The Skin-Whitening Effects of Ectoine via the Suppression of α-MSH-Stimulated Melanogenesis and the Activation of Antioxidant Nrf2 Pathways in UVA-Irradiated Keratinocytes
by: You-Cheng Hseu, et al.
Published: (2020-01-01) -
Pterostilbene Activates the Nrf2-Dependent Antioxidant Response to Ameliorate Arsenic-Induced Intracellular Damage and Apoptosis in Human Keratinocytes
by: Junfeng Zhou, et al.
Published: (2019-05-01) -
Enhancement of Anticancer Potential of Pterostilbene Derivative by Chalcone Hybridization
by: Kai-Wei Tang, et al.
Published: (2021-08-01) -
Activity of Pterostilbene Metabolites against Liver Steatosis in Cultured Hepatocytes
by: Jenifer Trepiana, et al.
Published: (2020-11-01) -
Design, Synthesis, and Anti-Bacterial Evaluation of Triazolyl-Pterostilbene Derivatives
by: Kai-Wei Tang, et al.
Published: (2019-09-01)