The in vitro and in vivo depigmenting activity of pterostilbene through induction of autophagy in melanocytes and inhibition of UVA-irradiated α-MSH in keratinocytes via Nrf2-mediated antioxidant pathways

The in vitro and in vivo depigmenting activity of pterostilbene through induction of autophagy in melanocytes and inhibition of UVA-irradiated α-MSH in keratinocytes via Nrf2-mediated antioxidant pathways

Pterostilbene (Pt) is a natural polyphenol found in blueberries and several grape varieties. Pt's pharmacological importance was well documented. Nevertheless, the depigmenting effects are not demonstrated. We evaluated the Pt's depigmenting effects through autophagy induction in B16F10 ce...

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Bibliographic Details
Main Authors: You-Cheng Hseu, PhD, Yugandhar Vudhya Gowrisankar, PhD, Li-Wei Wang, MS, Yan-Zhen Zhang, MS, Xuan-Zao Chen, MS, Pei-Jane Huang, PhD, Hung-Rong Yen, PhD, Hsin-Ling Yang, PhD
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:Redox Biology
Subjects:
Pterostilbene
ROS
Anti-melanogenesis
Nrf2
Autophagy
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231721001658

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http://www.sciencedirect.com/science/article/pii/S2213231721001658

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