Human placental mesenchymal stem cells ameliorate chemotherapy-induced damage in the testis by reducing apoptosis/oxidative stress and promoting autophagy

Human placental mesenchymal stem cells ameliorate chemotherapy-induced damage in the testis by reducing apoptosis/oxidative stress and promoting autophagy

Abstract Background The side effects of busulfan on male reproduction are serious, so fertility preservation in children undergoing busulfan treatment is a major worldwide concern. Human placental mesenchymal stem cells (hPMSCs) have advantages such as stable proliferation and lower immunogenicity t...

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Bibliographic Details
Main Authors: Jiafeng Lu, Zhenxing Liu, Mingkai Shu, Liya Zhang, Wenjuan Xia, Liuna Tang, Jincheng Li, Boxian Huang, Hong Li
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Stem Cell Research & Therapy
Subjects:
Busulfan
Spermatogenesis
Human placental mesenchymal stem cells
Autophagy
Reactive oxygen species
Apoptosis
Online Access:https://doi.org/10.1186/s13287-021-02275-z

Internet

https://doi.org/10.1186/s13287-021-02275-z

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