ALLOMETRIC ANALYSIS OF THE PHARMACOKINETICS OF FOUR CEPHALOSPORIN ANTIBIOTICS IN MAMMALS
Allometric analysis of the total body clearance (ClB), steady-state volume of distribution (Vss) and elimination half-life (t1/2) was performed for cephalexin, cefepime, cefquinone and ceftriaxone based on literature data in mammalian species. Values of ClB and Vss show allometric dependence on bod...
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| Format: | Article |
| Language: | English |
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Faculty of Veterinary Medicine, Trakia University, Stara Zagora, Bulgaria
2017-03-01
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| Series: | Bulgarian Journal of Veterinary Medicine |
| Online Access: | http://tru.uni-sz.bg/bjvm/BJVM-March%202017%20p.27-37.pdf |