Negative Regulatory Loop between Microphthalmia-Associated Transcription Factor (MITF) and Notch Signaling
Melanoma, a melanocyte-origin neoplasm, is a highly metastatic and treatment-resistance cancer. While it is well established that notch signaling activation promotes melanoma progression, little is known about the reciprocal interactions between Notch signaling and melanoma-specific pathways. Here w...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-01-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/20/3/576 |