Intranasal delivery of experimental compounds in orthotopic brain tumor mouse models

Summary: Effective therapeutics for malignant primary brain tumors, such as glioblastomas (GBMs), are urgently needed. To facilitate and expedite early-phase GBM therapeutic development, we describe a protocol that allows the intranasal delivery of experimental compounds in GBM orthotopic mouse mode...

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Bibliographic Details
Main Authors: Katharina M. Eyme, Litia Carvalho, Christian E. Badr
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S266616672030277X