The structure of a 15-stranded actin-like filament from Clostridium botulinum

The plasmid-segregating actin-like protein ParM is encoded on the large, toxin carrying plasmid pCBH from Clostridium botulinum. Here the authors present the cryo-EM structure of the ParM filament that is formed from the association of 15 protofilaments and discuss its architecture.

Bibliographic Details
Main Authors: Fujiet Koh, Akihiro Narita, Lin Jie Lee, Kotaro Tanaka, Yong Zi Tan, Venkata P. Dandey, David Popp, Robert C. Robinson
Format: Article
Language:English
Published: Nature Publishing Group 2019-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-10779-9