Prostaglandin (PG) F2 alpha synthesis in human subcutaneous and omental adipose tissue: modulation by inflammatory cytokines and role of the human aldose reductase AKR1B1.

PGF2α may be involved in the regulation of adipose tissue function.1) To examine PGF2α release by primary preadipocytes, mature adipocytes and whole tissue explants from the subcutaneous and omental fat compartments; 2) To assess which PGF synthase is the most relevant in human adipose tissue.Fat sa...

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Bibliographic Details
Main Authors: Andréanne Michaud, Nicolas Lacroix-Pépin, Mélissa Pelletier, Alain Veilleux, Suzanne Noël, Céline Bouchard, Picard Marceau, Michel A Fortier, André Tchernof
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3963845?pdf=render