The role of osteoclasts in breast cancer bone metastasis

Breast cancer frequently metastasises to the skeleton, interfering with the normal bone remodelling process and inducing bone degradation. Bone degradation is caused by osteoclasts, the normal bone-resorbing cells. Osteoclast-mediated bone degradation subsequently leads to the release of bone-derive...

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Bibliographic Details
Main Authors: François Le Pape, Geoffrey Vargas, Philippe Clézardin
Format: Article
Language:English
Published: Elsevier 2016-09-01
Series:Journal of Bone Oncology
Subjects:
OPG
Online Access:http://www.sciencedirect.com/science/article/pii/S2212137415300804