Discovery and validation of Barrett's esophagus microRNA transcriptome by next generation sequencing.

Barrett's esophagus (BE) is transition from squamous to columnar mucosa as a result of gastroesophageal reflux disease (GERD). The role of microRNA during this transition has not been systematically studied.For initial screening, total RNA from 5 GERD and 6 BE patients was size fractionated. RN...

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Bibliographic Details
Main Authors: Ajay Bansal, In-Hee Lee, Xiaoman Hong, Sharad C Mathur, Ossama Tawfik, Amit Rastogi, Navtej Buttar, Mahesh Visvanathan, Prateek Sharma, Lane K Christenson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3553128?pdf=render