Structural Biology of STAT3 and Its Implications for Anticancer Therapies Development

Structural Biology of STAT3 and Its Implications for Anticancer Therapies Development

Transcription factors are proteins able to bind DNA and induce the transcription of specific genes. Consequently, they play a pivotal role in multiple cellular pathways and are frequently over-expressed or dysregulated in cancer. Here, we will focus on a specific “signal transducer and act...

Full description

Bibliographic Details
Main Authors: Jacopo Sgrignani, Maura Garofalo, Milos Matkovic, Jessica Merulla, Carlo V. Catapano, Andrea Cavalli
Format: Article
Language:English
Published: MDPI AG 2018-05-01
Series:International Journal of Molecular Sciences
Subjects:
STAT3
cancer
molecular modeling
drug design
structural biology
Online Access:http://www.mdpi.com/1422-0067/19/6/1591

Internet

http://www.mdpi.com/1422-0067/19/6/1591

Similar Items