Phenotypic skewing of macrophages in vitro by secreted factors from colorectal cancer cells.

Macrophages are cells with many important functions in both innate and adaptive immune responses and have been shown to play a complex role in tumor progression since they harbour both tumor preventing (M1 macrophages) and tumor promoting (M2 macrophages) activities. In many human cancers, infiltrat...

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Bibliographic Details
Main Authors: Sofia Edin, Maria L Wikberg, Jörgen Rutegård, Per-Arne Oldenborg, Richard Palmqvist
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3776729?pdf=render