Correlation of the absorbed dose to the blood and DNA damage in leukocytes after internal ex-vivo irradiation of blood samples with Ra-224

Correlation of the absorbed dose to the blood and DNA damage in leukocytes after internal ex-vivo irradiation of blood samples with Ra-224

Abstract Background Irradiation with α-particles creates densely packed damage tracks along particle trajectories in exposed cells, including complex DNA damage and closely spaced double-strand breaks (DSBs) in hit nuclei. Here, we investigated the correlation of the absorbed dose to the blood and t...

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Bibliographic Details
Main Authors: Sarah Schumann, Uta Eberlein, Jessica Müller, Harry Scherthan, Michael Lassmann
Format: Article
Language:English
Published: SpringerOpen 2018-08-01
Series:EJNMMI Research
Subjects:
DNA damage
γ-H2AX
53BP1
Biological dosimetry
Absorbed dose to the blood
α-Emitter
Online Access:http://link.springer.com/article/10.1186/s13550-018-0422-4

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http://link.springer.com/article/10.1186/s13550-018-0422-4

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