CDK5RAP3 is a novel repressor of p14ARF in hepatocellular carcinoma cells.

CDK5 regulatory subunit associated protein 3 (CDK5RAP3) is a novel activator of PAK4 and processes important pro-metastatic function in hepatocarcinogenesis. However, it remains unclear if there are other mechanisms by which CDK5RAP3 promotes HCC metastasis. Here, we showed that in CDK5RAP3 stable k...

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Bibliographic Details
Main Authors: Grace Wing-Yan Mak, Wai-Lung Lai, Yuan Zhou, Mingtao Li, Irene Oi-Lin Ng, Yick-Pang Ching
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3409131?pdf=render