Female mice are protected against high-fat diet induced metabolic syndrome and increase the regulatory T cell population in adipose tissue.

Sex differences in obesity-induced complications such as type 2 diabetes have been reported. The aim of the study was to pinpoint the mechanisms resulting in different outcome of female and male mice on a high-fat diet (HFD). Mice fed control or HFD were monitored for weight, blood glucose, and insu...

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Bibliographic Details
Main Authors: Ulrika S Pettersson, Tomas B Waldén, Per-Ola Carlsson, Leif Jansson, Mia Phillipson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3458106?pdf=render