Reducing hypothalamic AGRP by RNA interference increases metabolic rate and decreases body weight without influencing food intake
<p>Abstract</p> <p>Background</p> <p>Several lines of evidence strongly suggest that agouti-related peptide (AGRP) plays a key role in the regulation of metabolic function but ablation of the AGRP gene has no apparent effect on metabolic function. Since specific pharmac...
Main Authors: | Mastaitis Jason W, Mizuno Tooru M, Makimura Hideo, Agami Reuven, Mobbs Charles V |
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Format: | Article |
Language: | English |
Published: |
BMC
2002-11-01
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Series: | BMC Neuroscience |
Online Access: | http://www.biomedcentral.com/1471-2202/3/18 |
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