Reducing hypothalamic AGRP by RNA interference increases metabolic rate and decreases body weight without influencing food intake

Reducing hypothalamic AGRP by RNA interference increases metabolic rate and decreases body weight without influencing food intake

<p>Abstract</p> <p>Background</p> <p>Several lines of evidence strongly suggest that agouti-related peptide (AGRP) plays a key role in the regulation of metabolic function but ablation of the AGRP gene has no apparent effect on metabolic function. Since specific pharmac...

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Bibliographic Details
Main Authors: Mastaitis Jason W, Mizuno Tooru M, Makimura Hideo, Agami Reuven, Mobbs Charles V
Format: Article
Language:English
Published: BMC 2002-11-01
Series:BMC Neuroscience
Online Access:http://www.biomedcentral.com/1471-2202/3/18

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http://www.biomedcentral.com/1471-2202/3/18

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