Neutrophil Extracellular Traps: A Perspective of Neuroinflammation and Complement Activation in Alzheimer’s Disease

Neutrophil Extracellular Traps: A Perspective of Neuroinflammation and Complement Activation in Alzheimer’s Disease

Complement system (CS) components are associated with Alzheimer’s disease (AD), the commonest cause of dementia in the world. Neutrophils can be attracted to amyloid-β plaques by several pro-inflammatory factors, including the complement anaphylatoxin C5a. They may release neutrophil extracellular t...

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Bibliographic Details
Main Authors: Gabriela Canalli Kretzschmar, Valéria Bumiller-Bini, Miguel Angelo Gasparetto Filho, Yohan Ricci Zonta, Kaio Shu Tsyr Yu, Ricardo Lehtonen R. de Souza, Luciane Alarcão Dias-Melicio, Angelica Beate Winter Boldt
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Molecular Biosciences
Subjects:
Alzheimer's Disease
neutrophil extracellular traps
inflammation
complement system
CR1
C5a
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.630869/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2021.630869/full

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