Immunogenic cell death in a combined synergic gene- and immune-therapy against cancer

It was previously demonstrated that engineered mesenchymal stem cells (MSCs) which express a high level of a very efficient modified gene CYP2B6* (CYP2B6TM-RED) acting as a suicide gene (MSC-2B6*) in combination with cyclophosphamide (CPA) constitute a powerful cell/gene therapy approach for solid t...

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Bibliographic Details
Main Authors: Benjamin Nayagom, Ikrame Amara, Meryem Habiballah, Floriane Amrouche, Philippe Beaune, Isabelle de Waziers
Format: Article
Language:English
Published: Taylor & Francis Group 2019-12-01
Series:OncoImmunology
Subjects:
Online Access:http://dx.doi.org/10.1080/2162402X.2019.1667743